Version 5.4
Mus musculus Gene: Cst11
Summary
InnateDB Gene IDBG-209095.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cst11
Gene Name cystatin 11
Synonyms 9230101F08Rik; BB067629; CRES2; mCSTE1
Species Mus musculus
Ensembl Gene ENSMUSG00000036958
Encoded Proteins
IDBP-209097
cystatin 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125831:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein whose specific function has not been determined. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:148768609-148771497
Strand Reverse strand
Band G3
Transcripts
ENSMUST00000028934 ENSMUSP00000028934
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004869 cysteine-type endopeptidase inhibitor activity
Biological Process
GO:0008150 biological_process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000125831
View Gene Order
Cross-References
SwissProt Q9D269
TrEMBL Q7M731
UniProt Splice Variant
Entrez Gene 78240
UniGene
RefSeq NM_030059
OMIM
CCDS CCDS16845
HPRD
IMGT
MGI ID MGI:1925490
MGI Symbol Cst11
EMBL AF454373 AK020300 BC100526 BK001265
GenPept AAI00527 AAL51004 BAB32061 DAA01199
RNA Seq Atlas 78240

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca