Version 5.4
Homo sapiens Gene: ADPGK
Summary
InnateDB Gene IDBG-20930.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADPGK
Gene Name ADP-dependent glucokinase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000159322
Encoded Proteins
IDBP-20932
ADP-dependent glucokinase
IDBP-377131
ADP-dependent glucokinase
IDBP-744822
IDBP-747127
IDBP-746455
IDBP-745791
IDBP-746336
IDBP-747663
IDBP-747271
IDBP-744679
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:72751369-72785846
Strand Reverse strand
Band q24.1
Transcripts
ENST00000311669 ENSP00000312250
ENST00000456471 ENSP00000397694
ENST00000562621
ENST00000567733
ENST00000566509
ENST00000565814 ENSP00000457447
ENST00000563907 ENSP00000456387
ENST00000569058
ENST00000569693 ENSP00000457572
ENST00000562823 ENSP00000454367
ENST00000562286 ENSP00000457175
ENST00000567941 ENSP00000458102
ENST00000569534 ENSP00000454707
ENST00000569517 ENSP00000454304
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0043843 ADP-specific glucokinase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process
GO:0016310 phosphorylation
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025236
View Gene Order
ENSBTAG00000001578
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.654636 Hs.741024
RefSeq NM_031284 XM_006720712 XM_006720713
HUGO
OMIM
CCDS CCDS42057
HPRD 12429
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca