InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Stard13

Summary

InnateDB Gene

IDBG-209686.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Stard13

Gene Name

StAR-related lipid transfer (START) domain containing 13

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000016128

Encoded Proteins

IDBP-209688

StAR-related lipid transfer (START) domain containing 13

IDBP-260183

StAR-related lipid transfer (START) domain containing 13

IDBP-535826

StAR-related lipid transfer (START) domain containing 13

IDBP-540536

StAR-related lipid transfer (START) domain containing 13

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133121:
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:151037628-151233836

Strand

Reverse strand

Band

Transcripts

ENSMUST00000062015	ENSMUSP00000053232
ENSMUST00000110483	ENSMUSP00000106109
ENSMUST00000129088	ENSMUSP00000116705
ENSMUST00000141117
ENSMUST00000146814
ENSMUST00000126770	ENSMUSP00000122468

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0005515	protein binding
GO:0008289	lipid binding

Biological Process

GO:0007049	cell cycle
GO:0007165	signal transduction
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005622	intracellular
GO:0005811	lipid particle
GO:0031966	mitochondrial membrane

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000133121

View Gene Order

ENSBTAG00000021815

Not yet available

Pathways

NETPATH

REACTOME

REACT_206918

Signaling by Rho GTPases pathway

REACT_210090

Rho GTPase cycle pathway

REACT_188257

Signal Transduction pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_11051

Rho GTPase cycle pathway

REACT_11044

Signaling by Rho GTPases pathway

REACT_111102

Signal Transduction pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

D3Z5Y1

UniProt Splice Variant

Entrez Gene

243362

UniGene

Mm.209272

RefSeq

NM_001163493 NM_146258 XM_006504918 XM_006504919 XM_006504920 XM_006504921 XM_006504922 XM_006504923 XM_006504925

OMIM

CCDS

CCDS19890 CCDS51710

HPRD

IMGT

MGI ID

MGI:2385331

MGI Symbol

Stard13

EMBL

AC109614 AC163219

GenPept

RNA Seq Atlas

243362