Version 5.4
Mus musculus Gene: Defb22
Summary
InnateDB Gene IDBG-209762.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Defb22
Gene Name defensin beta 22
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000027468
Encoded Proteins
IDBP-209764
defensin beta 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125788:
Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. The encoded protein is highly similar to an epididymal-specific secretory protein (ESP13.2) from cynomolgus monkey. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152485663-152490138
Strand Reverse strand
Band G3
Transcripts
ENSMUST00000028966 ENSMUSP00000028966
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
GO:0009986 cell surface
GO:0030112 glycocalyx
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000125788
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115897
Beta defensins pathway
REACT_115846
Defensins pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.99065
RefSeq NM_001002791
OMIM
CCDS CCDS16887
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca