Version 5.4
Mus musculus Gene: Hoxb7
Summary
InnateDB Gene IDBG-209880.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hoxb7
Gene Name homeobox B7
Synonyms AI325018; Hox-2.3
Species Mus musculus
Ensembl Gene ENSMUSG00000038721
Encoded Proteins
IDBP-209882
homeobox B7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:96286623-96290162
Strand Forward strand
Band D
Transcripts
ENSMUST00000049352 ENSMUSP00000040121
ENSMUST00000151596
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009952 anterior/posterior pattern specification
GO:0030099 myeloid cell differentiation
GO:0048704 embryonic skeletal system morphogenesis
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000005546
Not yet available
Cross-References
SwissProt P09024
TrEMBL
UniProt Splice Variant
Entrez Gene 15415
UniGene Mm.390366 Mm.402388
RefSeq NM_010460 XM_006532293
OMIM
CCDS CCDS25294
HPRD
IMGT
MGI ID MGI:96188
MGI Symbol Hoxb7
EMBL AK136706 AL645478 M18167 M18400 X06762 X14570 Y00436
GenPept AAA37845 AAA88245 BAE23104 CAA29934 CAA32708 CAA68494 CAM27142
RNA Seq Atlas 15415

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca