Version 5.4
Mus musculus Gene: Arhgap23
Summary
InnateDB Gene IDBG-210248.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap23
Gene Name Rho GTPase activating protein 23
Synonyms A330041B18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000049807
Encoded Proteins
IDBP-210252
Rho GTPase activating protein 23
IDBP-266324
Rho GTPase activating protein 23
IDBP-400072
Rho GTPase activating protein 23
IDBP-541235
Rho GTPase activating protein 23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:97415533-97502402
Strand Forward strand
Band D
Transcripts
ENSMUST00000093940 ENSMUSP00000091472
ENSMUST00000107601 ENSMUSP00000103227
ENSMUST00000121799 ENSMUSP00000112999
ENSMUST00000152933
ENSMUST00000142465 ENSMUSP00000123191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000016911
Not yet available
Pathways
NETPATH
REACTOME
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8VQ11
UniProt Splice Variant
Entrez Gene 58996
UniGene Mm.394118 Mm.486629
RefSeq NM_021493 XM_006533871 XM_006533861 XM_006533862 XM_006533864 XM_006533865 XM_006533866 XM_006533867 XM_006533874
OMIM
CCDS CCDS36293
HPRD
IMGT
MGI ID MGI:3697726
MGI Symbol Arhgap23
EMBL AL596088
GenPept
RNA Seq Atlas 58996

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca