Mus musculus Gene: Myl9

Summary
InnateDB Gene IDBG-210979.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol Myl9
Gene Name myosin, light polypeptide 9, regulatory
Synonyms AI327049; MLC20; Mylc2c; RLC-C
Species Mus musculus
Ensembl Gene ENSMUSG00000067818
Encoded Proteins
IDBP-210981 myosin, light polypeptide 9, regulatory
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101335:
Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2: 156775420-156781658
Strand Forward strand
Band H1
Transcripts
ENSMUST00000088552  ENSMUSP00000085913
ENSMUST00000145299 
ENSMUST00000132985 
ENSMUST00000131622 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
 
Predicted by orthology
Total 4 [view]
Gene Ontology
Accession GO Term
Molecular Function
GO:0005509 calcium ion binding
Biological Process
Cellular Component
GO:0001725 stress fiber
GO:0016460 myosin II complex
GO:0030018 Z disc
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSG00000101335 Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
ENSBTAG00000011473 Not yet available Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
REACT_133790 Sema4D induced cell migration and growth-cone collapse
REACT_81255 Smooth Muscle Contraction
KEGG
mmu04510  Focal adhesion
mmu04670  Leukocyte transendothelial migration
mmu04810  Regulation of actin cytoskeleton
mmu04530  Tight junction
mmu04270  Vascular smooth muscle contraction
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9 TNFalpha pathway
REACTOME
REACT_19277 Sema4D induced cell migration and growth-cone collapse
REACT_20558 Smooth Muscle Contraction
KEGG
hsa04510  Focal adhesion
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04530  Tight junction
hsa04270  Vascular smooth muscle contraction
INOH
PID BIOCARTA
PID NCI
ilk_pathway Integrin-linked kinase signaling
Cross-References
SwissProt Q9CQ19 
TrEMBL A2AVY6
UniProt Splice Variant
Entrez Gene 98932 
UniGene
RefSeq NM_172118 
OMIM
CCDS CCDS50779 
HPRD
IMGT
MGI ID MGI:2138915 
MGI Symbol Myl9
EMBL AK007972 AK020258 AK159880 AL935150 BC049974 BC055439 CH466551
GenPept AAH49974  AAH55439  BAB25381  BAB32043  BAE35452  CAM27933  EDL06205 
ImmGen Myl9 (murine) 
RNA Seq Atlas 98932