Version 5.4
Mus musculus Gene: Gast
Summary
InnateDB Gene IDBG-211331.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gast
Gene Name gastrin
Synonyms GAS
Species Mus musculus
Ensembl Gene ENSMUSG00000017165
Encoded Proteins
IDBP-211333
gastrin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184502:
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:100334407-100336996
Strand Forward strand
Band D
Transcripts
ENSMUST00000017309 ENSMUSP00000017309
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184502
View Gene Order
ENSBTAG00000017663
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04971
Gastric acid secretion pathway
INOH
INOH website
GPCR signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_205036
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_205369
Signaling by GPCR pathway
REACT_214353
Signal Transduction pathway
REACT_209521
G alpha (q) signalling events pathway
REACT_214436
GPCR downstream signaling pathway
KEGG
hsa04971
Gastric acid secretion pathway
INOH
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt P48757
TrEMBL Q9CTZ2
UniProt Splice Variant
Entrez Gene 14459
UniGene Mm.4767
RefSeq NM_010257
OMIM
CCDS CCDS25418
HPRD
IMGT
MGI ID MGI:104768
MGI Symbol Gast
EMBL AK008062 AK008159 AK008313 AK008420 AK008494 AK008649 AK019058 AL590968 U34293 U58136 X94758 X94760
GenPept AAB06947 AAB97872 BAB25437 BAB25501 BAB25596 BAB25658 BAB25699 BAB25807 BAB31528 CAA64385 CAA64386 CAM23027
RNA Seq Atlas 14459

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca