Version 5.4
Mus musculus Gene: Mki67
Summary
InnateDB Gene IDBG-211379.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mki67
Gene Name antigen identified by monoclonal antibody Ki 67
Synonyms D630048A14Rik; Ki-67; Ki67
Species Mus musculus
Ensembl Gene ENSMUSG00000031004
Encoded Proteins
IDBP-211381
antigen identified by monoclonal antibody Ki 67
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148773:
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:135689788-135716379
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000033310 ENSMUSP00000033310
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006259 DNA metabolic process
GO:0007126 meiotic nuclear division
GO:0008283 cell proliferation
GO:0014070 response to organic cyclic compound
GO:0030212 hyaluronan metabolic process
GO:0031100 organ regeneration
GO:0034605 cellular response to heat
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000793 condensed chromosome
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000148773
View Gene Order
ENSBTAG00000002444
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PVX6 Q7TSF6
UniProt Splice Variant
Entrez Gene 17345
UniGene Mm.4078
RefSeq NM_001081117 XM_006507411 XM_006507412 XM_006507413
OMIM
CCDS CCDS52421
HPRD
IMGT
MGI ID MGI:106035
MGI Symbol Mki67
EMBL AC123047 BC053453
GenPept AAH53453
RNA Seq Atlas 17345

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca