Version 5.4
Mus musculus Gene: Wfdc5
Summary
InnateDB Gene IDBG-212041.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wfdc5
Gene Name WAP four-disulfide core domain 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040154
Encoded Proteins
IDBP-212043
WAP four-disulfide core domain 5
IDBP-533260
WAP four-disulfide core domain 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175121:
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:164176327-164182742
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000045127 ENSMUSP00000035824
ENSMUST00000131974 ENSMUSP00000115448
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0008150 biological_process
GO:0010466 negative regulation of peptidase activity
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000175121
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.218273
RefSeq NM_145369
OMIM
CCDS CCDS17023
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca