Version 5.4
| Mus musculus Gene: Muc5b | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-212403.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Muc5b | ||||||||
| Gene Name | mucin 5, subtype B, tracheobronchial | ||||||||
| Synonyms | 2300002I04Rik; A130042M24; AV085033; MUC5; MUC9; mucin 5b | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000066108 | ||||||||
| Encoded Proteins |
mucin 5, subtype B, tracheobronchial
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117983:
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:141839070-141873084 | ||||||||
| Strand | Forward strand | ||||||||
| Band | F5 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Salivary secretion pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Termination of O-glycan biosynthesis pathway
O-linked glycosylation of mucins pathway
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
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| KEGG |
Salivary secretion pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E9Q5I3 Q8BYW0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 74180 | ||||||||
| UniGene | Mm.200752 | ||||||||
| RefSeq | NM_028801 XM_006508653 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS52448 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1921430 | ||||||||
| MGI Symbol | Muc5b | ||||||||
| EMBL | AC175742 AK037730 AL772165 | ||||||||
| GenPept | BAC29860 | ||||||||
| RNA Seq Atlas | 74180 | ||||||||