Version 5.4
Mus musculus Gene: Syt8
Summary
InnateDB Gene IDBG-212545.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Syt8
Gene Name synaptotagmin VIII
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031098
Encoded Proteins
IDBP-212549
synaptotagmin VIII
IDBP-269747
synaptotagmin VIII
IDBP-269749
synaptotagmin VIII
IDBP-400120
synaptotagmin VIII
IDBP-400121
synaptotagmin VIII
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149043:
Synaptotagmins, such as SYT8, share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains. Some synaptotagmins are involved in synaptic membrane fusion, while others have a more general function in endocytosis. For further information on synaptotagmins, see MIM 185605.[supplied by OMIM, May 2003]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:142434850-142440396
Strand Forward strand
Band F5
Transcripts
ENSMUST00000097939 ENSMUSP00000095552
ENSMUST00000105977 ENSMUSP00000101597
ENSMUST00000105976 ENSMUSP00000101596
ENSMUST00000122393 ENSMUSP00000112689
ENSMUST00000118276 ENSMUSP00000113545
ENSMUST00000150192
ENSMUST00000128481
ENSMUST00000148896
ENSMUST00000145964
ENSMUST00000124963
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0006810 transport
GO:0007340 acrosome reaction
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031988 membrane-bounded vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149043
View Gene Order
ENSBTAG00000040103
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.213002
RefSeq NM_001285857 NM_001285858 NM_001285861 NM_018802 XM_006508635 XM_006508636 XM_006508637
OMIM
CCDS CCDS22030 CCDS72070 CCDS72071
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca