Homo sapiens Gene: AMN

Summary
InnateDB Gene IDBG-21311.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol AMN
Gene Name amnionless homolog (mouse)
Synonyms amnionless; PRO1028
Species Homo sapiens
Ensembl Gene ENSG00000166126
Encoded Proteins
IDBP-21313 amnionless homolog (mouse)
IDBP-592964 amnionless homolog (mouse)
IDBP-583181 amnionless homolog (mouse)
Entrez Gene
Summary The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14: 103388993-103399933
Strand Forward strand
Band q32.32
Transcripts
ENST00000299155  ENSP00000299155
ENST00000541086 
ENST00000558590 
ENST00000559442 
ENST00000559525  ENSP00000453786
ENST00000559789  ENSP00000452831
ENST00000559507 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein‑Protein  1
[view]
Protein‑DNA 0
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Gene Ontology
Accession GO Term
Molecular Function
Biological Process
GO:0006629 lipid metabolic process
GO:0007275 multicellular organismal development
GO:0007588 excretion
GO:0008104 protein localization
GO:0042157 lipoprotein metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0045177 apical part of cell
Orthologs
Species
Mus musculus
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSMUSG00000021278 Ortholuge SSD Ortholog Ortholog supports species divergence
ENSBTAG00000015750 Not yet available Ortholuge SSD Ortholog Ortholog supports species divergence
Pathways
NETPATH
REACTOME
REACT_13621 HDL-mediated lipid transport
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9BXJ7 
TrEMBL B3KP64
UniProt Splice Variant
Entrez Gene 81693 
UniGene Hs.534494 Hs.709485
RefSeq NM_030943 
HUGO 14604 
OMIM 605799
CCDS CCDS9977 
HPRD 09314
IMGT
EMBL AF328788 AK055802 AL117209 AY358468 CH471061
GenPept AAK28532  AAQ89949  BAG51576  EAW81798 
ImmGen AMN (murine) 
RNA Seq Atlas 81693