Homo sapiens Gene: AMN
Summary
InnateDB Gene IDBG-21311.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol AMN
Gene Name amnionless homolog (mouse)
Synonyms amnionless; PRO1028;
Species Homo sapiens
Ensembl Gene ENSG00000166126
Encoded Proteins
amnionless homolog (mouse)
amnionless homolog (mouse)
amnionless homolog (mouse)
Protein Structure
Entrez Gene
Summary The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:103388993-103399933
Strand Forward strand
Band q32.32
Transcripts
ENST00000299155 ENSP00000299155
ENST00000541086
ENST00000558590
ENST00000559442
ENST00000559525 ENSP00000453786
ENST00000559789 ENSP00000452831
ENST00000559507
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006629 lipid metabolic process
GO:0007275 multicellular organismal development
GO:0007588 excretion
GO:0008104 protein localization
GO:0042157 lipoprotein metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0045177 apical part of cell
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
HDL-mediated lipid transport pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9BXJ7
TrEMBL B3KP64
UniProt Splice Variant
Entrez Gene 81693
UniGene Hs.534494 Hs.709485
RefSeq NM_030943
HUGO 14604
OMIM 605799
CCDS CCDS9977
HPRD 09314
IMGT
EMBL AF328788 AK055802 AL117209 AY358468 CH471061
GenPept AAK28532 AAQ89949 BAG51576 EAW81798
ImmGen AMN (murine)
RNA Seq Atlas 81693