Version 5.4
Mus musculus Gene: Cstf1
Summary
InnateDB Gene IDBG-213287.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cstf1
Gene Name cleavage stimulation factor, 3' pre-RNA, subunit 1
Synonyms 1700057K18Rik; AI788832
Species Mus musculus
Ensembl Gene ENSMUSG00000027498
Encoded Proteins
IDBP-274280
cleavage stimulation factor, 3' pre-RNA, subunit 1
IDBP-533081
cleavage stimulation factor, 3' pre-RNA, subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101138:
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3\'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5\' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:172370681-172382448
Strand Forward strand
Band H3
Transcripts
ENSMUST00000116375 ENSMUSP00000112076
ENSMUST00000151511 ENSMUSP00000121178
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101138
View Gene Order
ENSBTAG00000006639
Not yet available
Pathways
NETPATH
REACTOME
REACT_240247
mRNA 3'-end processing pathway
REACT_249110
mRNA Splicing pathway
REACT_248407
Processing of Capped Intronless Pre-mRNA pathway
REACT_232123
Processing of Intronless Pre-mRNAs pathway
REACT_257346
RNA Polymerase II Transcription Termination pathway
REACT_253727
Cleavage of Growing Transcript in the Termination Region pathway
REACT_233572
Gene Expression pathway
REACT_260226
mRNA Splicing - Major Pathway pathway
REACT_233950
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_242255
RNA Polymerase II Transcription pathway
KEGG
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1096
Processing of Intronless Pre-mRNAs pathway
REACT_1849
mRNA 3'-end processing pathway
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_387
Cleavage of Growing Transcript in the Termination Region pathway
REACT_894
RNA Polymerase II Transcription Termination pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_1768
Processing of Capped Intronless Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
bard1pathway
BARD1 signaling events
Cross-References
SwissProt
TrEMBL A2APA3
UniProt Splice Variant
Entrez Gene 67337
UniGene Mm.26944 Mm.409948 Mm.447539
RefSeq NM_024199 XM_006500072
OMIM
CCDS CCDS17130
HPRD
IMGT
MGI ID MGI:1914587
MGI Symbol Cstf1
EMBL AL833787
GenPept
RNA Seq Atlas 67337

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca