Mus musculus Gene: Tk1
Summary
InnateDB Gene IDBG-214587.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tk1
Gene Name thymidine kinase 1
Synonyms D530002A18Rik; Tk-1; Tk1a; Tk1b
Species Mus musculus
Ensembl Gene ENSMUSG00000025574
Encoded Proteins
thymidine kinase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167900:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:117815526-117826092
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026661 ENSMUSP00000026661
ENSMUST00000141939
ENSMUST00000153872
ENSMUST00000154790
ENSMUST00000153298
ENSMUST00000129852
ENSMUST00000150027
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 153 interaction(s) predicted by orthology.
Predicted by orthology
Total 153 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004797 thymidine kinase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0019206 nucleoside kinase activity
GO:0042802 identical protein binding
Biological Process
GO:0001889 liver development
GO:0006260 DNA replication
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0009636 response to toxic substance
GO:0014856 skeletal muscle cell proliferation
GO:0016310 phosphorylation
GO:0031667 response to nutrient levels
GO:0046104 thymidine metabolic process
GO:0046688 response to copper ion
GO:0048565 digestive tract development
GO:0051289 protein homotetramerization
GO:0051414 response to cortisol
GO:0060138 fetal process involved in parturition
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Pyrimidine metabolism pathway
Metabolism pathway
Pyrimidine salvage reactions pathway
Metabolism of nucleotides pathway
KEGG
Pyrimidine metabolism pathway
Drug metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pyrimidine salvage reactions pathway
Metabolism of nucleotides pathway
Pyrimidine metabolism pathway
Metabolism pathway
Pyrimidine metabolism pathway
Metabolism of nucleotides pathway
Metabolism pathway
Pyrimidine salvage reactions pathway
KEGG
Pyrimidine metabolism pathway
Drug metabolism pathway
INOH
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Validated targets of C-MYC transcriptional activation
E2F transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.443968
RefSeq NM_009387
OMIM
CCDS CCDS25692
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas