Version 5.4
Mus musculus Gene: Cant1
Summary
InnateDB Gene IDBG-214641.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cant1
Gene Name calcium activated nucleotidase 1
Synonyms 5830420C20Rik; Apy1h; D11Bwg0554e; Entpd8; SCAN-1; Shapy
Species Mus musculus
Ensembl Gene ENSMUSG00000025575
Encoded Proteins
IDBP-214643
calcium activated nucleotidase 1
IDBP-214645
calcium activated nucleotidase 1
IDBP-269079
calcium activated nucleotidase 1
IDBP-269081
calcium activated nucleotidase 1
IDBP-269083
calcium activated nucleotidase 1
IDBP-623615
calcium activated nucleotidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a calcium-dependent nucleotidase that preferentially hydrolyzes UDP, GDP, and IDP. The encoded protein has low activity with ADP and ATP and shows no activity with AMP and GMP. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:118406289-118419086
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000017620 ENSMUSP00000017620
ENSMUST00000092378 ENSMUSP00000090032
ENSMUST00000106289 ENSMUSP00000101896
ENSMUST00000106288 ENSMUSP00000101895
ENSMUST00000106287 ENSMUSP00000101894
ENSMUST00000164927 ENSMUSP00000126919
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004382 guanosine-diphosphatase activity
GO:0004871 signal transducer activity
GO:0005509 calcium ion binding
GO:0016462 pyrophosphatase activity
GO:0045134 uridine-diphosphatase activity
Biological Process
GO:0007165 signal transduction
GO:0009191 ribonucleoside diphosphate catabolic process
GO:0030166 proteoglycan biosynthetic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171302
View Gene Order
ENSBTAG00000009991
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt Q8VCF1
TrEMBL
UniProt Splice Variant
Entrez Gene 76025
UniGene Mm.177551 Mm.445714 Mm.473491
RefSeq XM_006534411 NM_001025617 NM_001025618 NM_001267591 NM_001267592 NM_029502 XM_006534404 XM_006534405 XM_006534406 XM_006534407 XM_006534408 XM_006534409 XM_006534410
OMIM
CCDS CCDS25702 CCDS59572
HPRD
IMGT
MGI ID MGI:1923275
MGI Symbol Cant1
EMBL AK006565 AK017942 AK049879 AK081118 AK085059 AL591404 BC020003
GenPept AAH20003 BAB24655 BAB31014 BAC33968 BAC38139 BAC39351 CAM23112
RNA Seq Atlas 76025

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca