Version 5.4
Mus musculus Gene: Cbx8
Summary
InnateDB Gene IDBG-214668.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cbx8
Gene Name chromobox 8
Synonyms Pc3
Species Mus musculus
Ensembl Gene ENSMUSG00000025578
Encoded Proteins
IDBP-214670
chromobox homolog 8 (Drosophila Pc class)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141570:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:119036305-119040969
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026663 ENSMUSP00000026663
ENSMUST00000128019
ENSMUST00000143831
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 79 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 79 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003727 single-stranded RNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0035064 methylated histone binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006342 chromatin silencing
GO:0006351 transcription, DNA-templated
GO:0016574 histone ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0000790 nuclear chromatin
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141570
View Gene Order
ENSBTAG00000009107
Not yet available
Pathways
NETPATH
REACTOME
REACT_188970
Oxidative Stress Induced Senescence pathway
REACT_188957
Cellular responses to stress pathway
REACT_188820
Cellular Senescence pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_169274
Cellular Senescence pathway
REACT_169436
Oxidative Stress Induced Senescence pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.406258 Mm.442809 Mm.99953
RefSeq NM_013926 XM_006533519
OMIM
CCDS CCDS25709
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca