Version 5.4
Mus musculus Gene: Eif4a3
Summary
InnateDB Gene IDBG-214689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif4a3
Gene Name eukaryotic translation initiation factor 4A3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025580
Encoded Proteins
IDBP-214691
eukaryotic translation initiation factor 4A3
IDBP-269155
eukaryotic translation initiation factor 4A3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:119288363-119300089
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026667 ENSMUSP00000026667
ENSMUST00000106253 ENSMUSP00000101860
ENSMUST00000129044
ENSMUST00000138849
ENSMUST00000135294
ENSMUST00000134743
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006200 ATP catabolic process
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0006417 regulation of translation
GO:0008380 RNA splicing
GO:0051028 mRNA transport
Cellular Component
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu03040
Spliceosome pathway
mmu03013
RNA transport pathway
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.197555 Mm.391505 Mm.417085 Mm.422975 Mm.490978
RefSeq NM_138669 XM_006544058 XM_485792
OMIM
CCDS CCDS25714
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca