Version 5.4
Mus musculus Gene: Rnf213
Summary
InnateDB Gene IDBG-214708.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf213
Gene Name ring finger protein 213
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000070327
Encoded Proteins
IDBP-214714
ring finger protein 213
IDBP-538083
ring finger protein 213
IDBP-623787
ring finger protein 213
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173821:
This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:119393100-119487418
Strand Forward strand
Band E2
Transcripts
ENSMUST00000093902 ENSMUSP00000091429
ENSMUST00000131035 ENSMUSP00000115063
ENSMUST00000172235 ENSMUSP00000130027
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0016567 protein ubiquitination
GO:0051865 protein autoubiquitination
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173821
View Gene Order
ENSBTAG00000022489
Not yet available
Cross-References
SwissProt
TrEMBL Q3U0U2 Q3UD49
UniProt Splice Variant
Entrez Gene 672511
UniGene
RefSeq XM_006534630 XM_006534631 XM_006534632 XM_006534633 XM_006542916 XM_006542917 XM_006542918 XM_006542919
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:1289196
MGI Symbol Rnf213
EMBL AK150249 AK156571 AL645911
GenPept BAE29413 BAE33759
RNA Seq Atlas 672511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca