Version 5.4
Mus musculus Gene: Aspscr1
Summary
InnateDB Gene IDBG-214877.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aspscr1
Gene Name alveolar soft part sarcoma chromosome region, candidate 1 (human)
Synonyms 1190006K01Rik; ASPC; ASPCR1; ASPL; ASPS; RCC17; TUG
Species Mus musculus
Ensembl Gene ENSMUSG00000025142
Encoded Proteins
IDBP-214879
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-214881
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-269316
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-269318
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-269320
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-532270
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-624338
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-535524
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-539249
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-538940
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-542706
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-533691
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-531746
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-624335
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-624336
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-624343
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-624346
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-624348
alveolar soft part sarcoma chromosome region, candidate 1 (human)
IDBP-624350
alveolar soft part sarcoma chromosome region, candidate 1 (human)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169696:
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120672973-120709447
Strand Forward strand
Band E2
Transcripts
ENSMUST00000026135 ENSMUSP00000026135
ENSMUST00000103016 ENSMUSP00000099305
ENSMUST00000106160 ENSMUSP00000101766
ENSMUST00000106159 ENSMUSP00000101765
ENSMUST00000106158 ENSMUSP00000101764
ENSMUST00000135346 ENSMUSP00000120072
ENSMUST00000143844 ENSMUSP00000129320
ENSMUST00000127269 ENSMUSP00000123650
ENSMUST00000131727 ENSMUSP00000117654
ENSMUST00000149389 ENSMUSP00000122216
ENSMUST00000153346 ENSMUSP00000120669
ENSMUST00000129644 ENSMUSP00000117353
ENSMUST00000151160 ENSMUSP00000116447
ENSMUST00000152990
ENSMUST00000151531
ENSMUST00000169964
ENSMUST00000171700
ENSMUST00000168097 ENSMUSP00000130303
ENSMUST00000168714 ENSMUSP00000129462
ENSMUST00000168510 ENSMUSP00000125931
ENSMUST00000166838 ENSMUSP00000127202
ENSMUST00000167678 ENSMUSP00000128940
ENSMUST00000168947 ENSMUSP00000125851
ENSMUST00000172392
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0042593 glucose homeostasis
GO:0046324 regulation of glucose import
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0009898 cytoplasmic side of plasma membrane
GO:0012505 endomembrane system
GO:0012506 vesicle membrane
GO:0019898 extrinsic component of membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169696
View Gene Order
ENSBTAG00000004632
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_199054
Translocation of GLUT4 to the plasma membrane pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.294020
RefSeq NM_001164224 NM_026877 NM_198223 XM_006534084 XM_006534085 XM_006534086 XM_006534087
OMIM
CCDS CCDS25751 CCDS25752 CCDS49008
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca