Version 5.4
Homo sapiens Gene: UGT2B4
Summary
InnateDB Gene IDBG-21870.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UGT2B4
Gene Name UDP glucuronosyltransferase 2 family, polypeptide B4
Synonyms HLUG25; UDPGT2B4; UDPGTh-1; UDPGTH1; UGT2B11
Species Homo sapiens
Ensembl Gene ENSG00000156096
Encoded Proteins
IDBP-21872
UDP glucuronosyltransferase 2 family, polypeptide B4
IDBP-477796
UDP glucuronosyltransferase 2 family, polypeptide B4
IDBP-477297
UDP glucuronosyltransferase 2 family, polypeptide B4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:69480165-69526014
Strand Reverse strand
Band q13.3
Transcripts
ENST00000305107 ENSP00000305221
ENST00000512583 ENSP00000421290
ENST00000506580
ENST00000502655
ENST00000503836
ENST00000510114 ENSP00000421113
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015020 glucuronosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006711 estrogen catabolic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0030259 lipid glycosylation
GO:0052695 cellular glucuronidation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_6784
Glucuronidation pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
KEGG
hsa00830
Retinol metabolism pathway
hsa00040
Pentose and glucuronate interconversions pathway
hsa00500
Starch and sucrose metabolism pathway
hsa00140
Steroid hormone biosynthesis pathway
hsa00053
Ascorbate and aldarate metabolism pathway
hsa00980
Metabolism of xenobiotics by cytochrome P450 pathway
hsa00860
Porphyrin and chlorophyll metabolism pathway
hsa00982
Drug metabolism pathway
hsa00983
Drug metabolism pathway
hsa04976
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.285887 Hs.603001 Hs.737169
RefSeq NM_001297615 NM_021139 XM_005265700
HUGO
OMIM
CCDS CCDS43234 CCDS75137
HPRD 02507
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca