Version 5.4
Homo sapiens Gene: UBE2E2
Summary
InnateDB Gene IDBG-22010.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE2E2
Gene Name ubiquitin-conjugating enzyme E2E 2
Synonyms UBCH8
Species Homo sapiens
Ensembl Gene ENSG00000182247
Encoded Proteins
IDBP-22012
ubiquitin-conjugating enzyme E2E 2
IDBP-236948
ubiquitin-conjugating enzyme E2E 2
IDBP-367614
ubiquitin-conjugating enzyme E2E 2
IDBP-367618
ubiquitin-conjugating enzyme E2E 2
IDBP-367628
ubiquitin-conjugating enzyme E2E 2
IDBP-810974
ubiquitin-conjugating enzyme E2E 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:23203020-23591793
Strand Forward strand
Band p24.3
Transcripts
ENST00000335798 ENSP00000338340
ENST00000396703 ENSP00000379931
ENST00000425792 ENSP00000401053
ENST00000452894 ENSP00000392800
ENST00000427371 ENSP00000407501
ENST00000613545 ENSP00000484777
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 81 experimentally validated interaction(s) in this database.
Experimentally validated
Total 81 [view]
Protein-Protein 81 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
GO:0042296 ISG15 ligase activity
Biological Process
GO:0008152 metabolic process
GO:0032020 ISG15-protein conjugation
GO:0070534 protein K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0070979 protein K11-linked ubiquitination
Cellular Component
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000058317
View Gene Order
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.475688 Hs.595802 Hs.598986
RefSeq NM_152653 XM_005265432
HUGO
OMIM
CCDS CCDS2637
HPRD 06779
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca