Version 5.4
Homo sapiens Gene: ULK3
Summary
InnateDB Gene IDBG-22723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ULK3
Gene Name unc-51-like kinase 3 (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140474
Encoded Proteins
IDBP-377894
unc-51-like kinase 3 (C. elegans)
IDBP-747059
IDBP-746145
IDBP-746553
IDBP-747833
IDBP-745206
IDBP-747594
IDBP-746038
IDBP-747438
IDBP-744910
IDBP-746756
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:74836116-74843346
Strand Reverse strand
Band q24.1
Transcripts
ENST00000440863 ENSP00000400312
ENST00000566631 ENSP00000455395
ENST00000565373 ENSP00000457983
ENST00000561725
ENST00000568210 ENSP00000456296
ENST00000562161 ENSP00000456510
ENST00000568679 ENSP00000455199
ENST00000564029
ENST00000569437 ENSP00000456051
ENST00000569813
ENST00000565790 ENSP00000457305
ENST00000568667 ENSP00000457853
ENST00000570276
ENST00000566479
ENST00000562395
ENST00000563301 ENSP00000457061
ENST00000568273 ENSP00000454583
ENST00000567472
ENST00000564767
ENST00000565881
ENST00000565011
ENST00000568718
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0000045 autophagic vacuole assembly
GO:0006468 protein phosphorylation
GO:0006914 autophagy
GO:0008152 metabolic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0010506 regulation of autophagy
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045880 positive regulation of smoothened signaling pathway
GO:0046777 protein autophosphorylation
GO:0090398 cellular senescence
Cellular Component
GO:0000407 pre-autophagosomal structure
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0034273 ATG1/UKL1 signaling complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032308
View Gene Order
ENSBTAG00000005838
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04150
mTOR signaling pathway pathway
hsa04140
Regulation of autophagy pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.513034
RefSeq NM_001099436 NM_001284364 NM_001284365 XM_005254289 XM_005254290
HUGO
OMIM
CCDS
HPRD 15609
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca