Homo sapiens Gene: MYL5

Summary
InnateDB Gene IDBG-228913.4
Last Modified 2011-02-17   [Report errors or provide feedback]
Gene Symbol MYL5
Gene Name myosin, light chain 5, regulatory
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000215375
Encoded Proteins
IDBP-228915 myosin, light chain 5, regulatory
IDBP-480096 myosin, light chain 5, regulatory
IDBP-479552 myosin, light chain 5, regulatory
IDBP-474967 myosin, light chain 5, regulatory
IDBP-476683 myosin, light chain 5, regulatory
IDBP-475484 myosin, light chain 5, regulatory
IDBP-483312 myosin, light chain 5, regulatory
Entrez Gene
Summary This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4: 667369-675822
Strand Forward strand
Band p16.3
Transcripts
ENST00000400159  ENSP00000383023
ENST00000506838  ENSP00000427153
ENST00000505477  ENSP00000423118
ENST00000503300  ENSP00000424528
ENST00000502720 
ENST00000511290  ENSP00000425162
ENST00000513662  ENSP00000423053
ENST00000507804  ENSP00000427317
ENST00000503612 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein‑Protein  3
[view]
Protein‑DNA 0
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0005509 calcium ion binding
GO:0008307 structural constituent of muscle
Biological Process
GO:0006937 regulation of muscle contraction
Cellular Component
GO:0005859 muscle myosin complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa04510  Focal adhesion
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04530  Tight junction
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q02045 
TrEMBL D6RA88 D6RB15 D6RJ91
UniProt Splice Variant
Entrez Gene 4636 
UniGene Hs.410970 Hs.739122
RefSeq NM_002477 
HUGO 7586 
OMIM 160782
CCDS CCDS43197 
HPRD 01182
IMGT
EMBL AC107464 BC040050 L03785
GenPept AAA59890  AAH40050 
ImmGen MYL5 (murine) 
RNA Seq Atlas 4636