Version 5.4
Homo sapiens Gene: CLEC10A
Summary
InnateDB Gene IDBG-23148.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC10A
Gene Name C-type lectin domain family 10, member A
Synonyms CD301; CLECSF13; CLECSF14; HML; HML2; MGL
Species Homo sapiens
Ensembl Gene ENSG00000132514
Encoded Proteins
IDBP-23152
C-type lectin domain family 10, member A
IDBP-364722
C-type lectin domain family 10, member A
IDBP-760518
IDBP-759104
IDBP-758232
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:7074537-7080307
Strand Reverse strand
Band p13.1
Transcripts
ENST00000254868 ENSP00000254868
ENST00000416562 ENSP00000414938
ENST00000571624
ENST00000576549 ENSP00000461800
ENST00000571664 ENSP00000460252
ENST00000576617 ENSP00000458728
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
GO:0006897 endocytosis
GO:0045087 innate immune response
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8IUN9
TrEMBL
UniProt Splice Variant
Entrez Gene 10462
UniGene Hs.54403
RefSeq NM_182906 XM_005256411 NM_006344 XM_005256412
HUGO HGNC:16916
OMIM 605999
CCDS CCDS11087 CCDS45597
HPRD 12076
IMGT
EMBL AK292363 BC027858 BC039011 D50532
GenPept AAH27858 AAH39011 BAA09101 BAF85052
RNA Seq Atlas 10462

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca