Homo sapiens Gene: RBMS3
Summary
InnateDB Gene IDBG-23267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBMS3
Gene Name RNA binding motif, single stranded interacting protein 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144642
Encoded Proteins
RNA binding motif, single stranded interacting protein 3
RNA binding motif, single stranded interacting protein 3
RNA binding motif, single stranded interacting protein 3
RNA binding motif, single stranded interacting protein 3
RNA binding motif, single stranded interacting protein 3
RNA binding motif, single stranded interacting protein 3
RNA binding motif, single stranded interacting protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:29280982-30010391
Strand Forward strand
Band p24.1
Transcripts
ENST00000383767 ENSP00000373277
ENST00000383766 ENSP00000373276
ENST00000273139 ENSP00000273139
ENST00000434693 ENSP00000395592
ENST00000445033 ENSP00000391934
ENST00000452462 ENSP00000397926
ENST00000456853 ENSP00000400519
ENST00000471426
ENST00000497205
ENST00000478716
ENST00000497319
ENST00000473799
ENST00000497274
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
Biological Process
GO:0045727 positive regulation of translation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL C9JIJ9
UniProt Splice Variant
Entrez Gene 27303
UniGene Hs.594906 Hs.621040 Hs.705969 Hs.742275
RefSeq XM_005265060 XM_005265063 XM_005265064 XM_005265065 XM_006713108 NM_001003792 NM_001003793 NM_001177711 NM_001177712 NM_014483
HUGO HGNC:13427
OMIM 605786
CCDS CCDS33724 CCDS33725 CCDS33726 CCDS54557 CCDS54558
HPRD 16155
IMGT
EMBL AC012262 AC021068 AC092795 AC092796 AC097633 AC098650 AC099048
GenPept
RNA Seq Atlas 27303