Version 5.4
Homo sapiens Gene: NEURL1B
Summary
InnateDB Gene IDBG-233717.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEURL1B
Gene Name neuralized homolog 1B (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000214357
Encoded Proteins
IDBP-100934
neuralized homolog 1B (Drosophila)
IDBP-484341
neuralized homolog 1B (Drosophila)
IDBP-473724
neuralized homolog 1B (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:172641266-172691540
Strand Forward strand
Band q35.1
Transcripts
ENST00000369800 ENSP00000358815
ENST00000520919 ENSP00000429797
ENST00000522853 ENSP00000430001
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0007219 Notch signaling pathway
GO:0016567 protein ubiquitination
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034413
View Gene Order
ENSBTAG00000001429
Not yet available
Pathways
NETPATH
REACTOME
REACT_118614
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_160205
NOTCH2 Activation and Transmission of Signal to the Nucleus pathway
REACT_160089
Constitutive Signaling by NOTCH1 HD Domain Mutants pathway
REACT_160243
Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway
REACT_160254
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway
REACT_160082
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_160214
Signaling by NOTCH1 in Cancer pathway
REACT_160099
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_118721
Signaling by NOTCH2 pathway
REACT_160301
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_160248
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_299
Signaling by NOTCH pathway
REACT_118859
Signaling by NOTCH1 pathway
REACT_160133
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt A8MQ27
TrEMBL
UniProt Splice Variant
Entrez Gene 54492
UniGene Hs.91521
RefSeq NM_001142651
HUGO HGNC:35422
OMIM 615893
CCDS CCDS47342
HPRD
IMGT
EMBL AC027309 GQ414757 GQ414758 GQ414759
GenPept ACV53563 ACV53564 ACV53565
RNA Seq Atlas 54492

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca