Version 5.4
Homo sapiens Gene: MTFR1
Summary
InnateDB Gene IDBG-23525.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTFR1
Gene Name mitochondrial fission regulator 1
Synonyms CHPPR; FAM54A2
Species Homo sapiens
Ensembl Gene ENSG00000066855
Encoded Proteins
IDBP-23527
mitochondrial fission regulator 1
IDBP-371517
mitochondrial fission regulator 1
IDBP-482094
mitochondrial fission regulator 1
IDBP-478571
mitochondrial fission regulator 1
IDBP-484935
mitochondrial fission regulator 1
IDBP-590898
mitochondrial fission regulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:65644734-65771261
Strand Forward strand
Band q13.1
Transcripts
ENST00000262146 ENSP00000262146
ENST00000458689 ENSP00000391502
ENST00000424808
ENST00000523170
ENST00000523222 ENSP00000429450
ENST00000522239
ENST00000517944
ENST00000518800 ENSP00000430621
ENST00000518636
ENST00000521247 ENSP00000429253
ENST00000518352
ENST00000523158
ENST00000520398
ENST00000527155 ENSP00000436928
ENST00000527553
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000266 mitochondrial fission
GO:0007005 mitochondrion organization
GO:0009060 aerobic respiration
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027601
View Gene Order
ENSBTAG00000008629
Not yet available
Cross-References
SwissProt
TrEMBL H7C5V5
UniProt Splice Variant
Entrez Gene 9650
UniGene Hs.584788 Hs.618542 Hs.729165
RefSeq NM_001145838 NM_014637 XM_005251327
HUGO HGNC:29510
OMIM
CCDS CCDS55240 CCDS6182
HPRD 12389
IMGT
EMBL AC055822
GenPept
RNA Seq Atlas 9650

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca