Version 5.4
Homo sapiens Gene: UBD
Summary
InnateDB Gene IDBG-236915.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBD
Gene Name ubiquitin D
Synonyms FAT10; GABBR1; UBD-3
Species Homo sapiens
Ensembl Gene ENSG00000213886
Encoded Proteins
IDBP-72961
ubiquitin D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 19959714
UBD mediates NF-kappaB activation and may promote tubulointerstitial inflammation in chronic kidney diseases.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:29555515-29559925
Strand Reverse strand
Band p22.1
Transcripts
ENST00000377050 ENSP00000366249
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 663 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 663 [view]
Protein-Protein 663 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0070628 proteasome binding
Biological Process
GO:0006508 proteolysis
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010243 response to organonitrogen compound
GO:0016567 protein ubiquitination
GO:0032446 protein modification by small protein conjugation
GO:0034341 response to interferon-gamma
GO:0034612 response to tumor necrosis factor
GO:0043011 myeloid dendritic cell differentiation
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response (InnateDB)
GO:0070842 aggresome assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016235 aggresome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000035186
View Gene Order
Cross-References
SwissProt O15205
TrEMBL
UniProt Splice Variant
Entrez Gene 10537
UniGene Hs.44532 Hs.743475
RefSeq NM_006398
HUGO HGNC:18795
OMIM 606050
CCDS CCDS4662
HPRD 09354
IMGT
EMBL AF123050 AL031983 AL645936 AL662826 BC012472 CH471081 CR759766 CR759770 CR942274 Y12653
GenPept AAD52982 AAH12472 CAA21458 CAA73200 CAI17384 CAI18010 CAQ06603 CAQ10041 CAQ10316 EAX03201
RNA Seq Atlas 10537

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca