Version 5.4
Homo sapiens Gene: KRTAP2-4
Summary
InnateDB Gene IDBG-242453.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRTAP2-4
Gene Name keratin associated protein 2-4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213417
Encoded Proteins
IDBP-242455
keratin associated protein 2-4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:41065116-41065879
Strand Reverse strand
Band q21.2
Transcripts
ENST00000394015 ENSP00000377583
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0045095 keratin filament
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q9BYR9
TrEMBL Q9BYS0
UniProt Splice Variant
Entrez Gene 85294
UniGene Hs.560502
RefSeq NM_033184
HUGO HGNC:18891
OMIM
CCDS CCDS32648
HPRD 13936
IMGT
EMBL AC100808 AJ406929 AJ406930 BC063625 BC101147 BC101148 BC101149
GenPept AAH63625 AAI01148 AAI01149 AAI01150 CAC27568 CAC27569
RNA Seq Atlas 730755 85294

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca