Version 5.4
Homo sapiens Gene: KRTAP4-12
Summary
InnateDB Gene IDBG-242461.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRTAP4-12
Gene Name keratin associated protein 4-12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213416
Encoded Proteins
IDBP-242463
keratin associated protein 4-12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:41123091-41124167
Strand Reverse strand
Band q21.2
Transcripts
ENST00000394014 ENSP00000377582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 82 experimentally validated interaction(s) in this database.
Experimentally validated
Total 82 [view]
Protein-Protein 82 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0045095 keratin filament
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q9BQ66
TrEMBL
UniProt Splice Variant
Entrez Gene 83755
UniGene Hs.572443
RefSeq NM_031854
HUGO HGNC:16776
OMIM
CCDS CCDS32649
HPRD 13941
IMGT
EMBL AC100808 AJ406943 BC004180 BC004212 BC101159 BC101160 BC101162
GenPept AAH04180 AAH04212 AAI01160 AAI01161 AAI01163 CAC27582
RNA Seq Atlas 83755

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca