Version 5.4
Homo sapiens Gene: OR2F1
Summary
InnateDB Gene IDBG-244723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR2F1
Gene Name olfactory receptor, family 2, subfamily F, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213215
Encoded Proteins
IDBP-244725
olfactory receptor, family 2, subfamily F, member 1
IDBP-808261
olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type polymorphic_pseudogene
Genomic Location Chromosome 7:143959927-143961015
Strand Forward strand
Band q35
Transcripts
ENST00000392899 ENSP00000376633
ENST00000624504 ENSP00000485483
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_15488
Olfactory Signaling Pathway pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q13607
TrEMBL
UniProt Splice Variant
Entrez Gene 26211
UniGene Hs.553595
RefSeq NM_012369
HUGO HGNC:8246
OMIM 608497
CCDS CCDS5887
HPRD
IMGT
EMBL AC004853 AF399594 BC104975 BK004215 CH236959 CH878732 U56421
GenPept AAB01215 AAC64376 AAI04976 AAK95079 DAA04613 EAL23795 EAW55625
RNA Seq Atlas 26211

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca