Version 5.4
Homo sapiens Gene: CRYZL1
Summary
InnateDB Gene IDBG-2459.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRYZL1
Gene Name crystallin, zeta (quinone reductase)-like 1
Synonyms 4P11; QOH-1
Species Homo sapiens
Ensembl Gene ENSG00000205758
Encoded Proteins
IDBP-2461
crystallin, zeta (quinone reductase)-like 1
IDBP-2465
crystallin, zeta (quinone reductase)-like 1
IDBP-2467
crystallin, zeta (quinone reductase)-like 1
IDBP-2469
crystallin, zeta (quinone reductase)-like 1
IDBP-230610
crystallin, zeta (quinone reductase)-like 1
IDBP-363400
crystallin, zeta (quinone reductase)-like 1
IDBP-363401
crystallin, zeta (quinone reductase)-like 1
IDBP-363403
crystallin, zeta (quinone reductase)-like 1
IDBP-363405
crystallin, zeta (quinone reductase)-like 1
IDBP-363413
crystallin, zeta (quinone reductase)-like 1
IDBP-363414
crystallin, zeta (quinone reductase)-like 1
IDBP-363419
crystallin, zeta (quinone reductase)-like 1
IDBP-363423
crystallin, zeta (quinone reductase)-like 1
IDBP-363426
crystallin, zeta (quinone reductase)-like 1
IDBP-363431
crystallin, zeta (quinone reductase)-like 1
IDBP-363433
crystallin, zeta (quinone reductase)-like 1
IDBP-363434
crystallin, zeta (quinone reductase)-like 1
IDBP-363436
crystallin, zeta (quinone reductase)-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:33589341-33643926
Strand Reverse strand
Band q22.11
Transcripts
ENST00000381554 ENSP00000370966
ENST00000361534 ENSP00000355075
ENST00000290244 ENSP00000290244
ENST00000381540 ENSP00000370951
ENST00000399442 ENSP00000382371
ENST00000452420 ENSP00000413513
ENST00000441940 ENSP00000397318
ENST00000445393 ENSP00000399730
ENST00000437996 ENSP00000406423
ENST00000429827 ENSP00000399937
ENST00000420072 ENSP00000416315
ENST00000440526 ENSP00000412087
ENST00000414079 ENSP00000409387
ENST00000426935 ENSP00000387660
ENST00000431177 ENSP00000405510
ENST00000417979 ENSP00000402844
ENST00000413017 ENSP00000389209
ENST00000438788 ENSP00000408385
ENST00000468349
ENST00000480893
ENST00000479964
ENST00000488167
ENST00000490714
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003960 NADPH:quinone reductase activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0050661 NADP binding
Biological Process
GO:0055114 oxidation-reduction process
GO:1901661 quinone metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000058240
View Gene Order
ENSBTAG00000008490
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 9946
UniGene Hs.352671 Hs.603515 Hs.695133
RefSeq NM_145858
HUGO HGNC:2420
OMIM 603920
CCDS CCDS13633
HPRD 06797
IMGT
EMBL
GenPept
RNA Seq Atlas 9946

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca