Version 5.4
Homo sapiens Gene: ZNF254
Summary
InnateDB Gene IDBG-245976.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF254
Gene Name zinc finger protein 254
Synonyms BMZF-5; HD-ZNF1; ZNF539; ZNF91L
Species Homo sapiens
Ensembl Gene ENSG00000213096
Encoded Proteins
IDBP-599762
zinc finger protein 254
IDBP-41608
zinc finger protein 254
IDBP-41610
zinc finger protein 254
IDBP-763310
IDBP-764784
IDBP-810973
zinc finger protein 254
IDBP-810981
zinc finger protein 254
IDBP-810984
zinc finger protein 254
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, Jul 2002]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:24033405-24129961
Strand Forward strand
Band p12
Transcripts
ENST00000342944 ENSP00000445527
ENST00000357002 ENSP00000349494
ENST00000339642 ENSP00000341573
ENST00000595187 ENSP00000472863
ENST00000593783
ENST00000594886 ENSP00000470845
ENST00000616028 ENSP00000484930
ENST00000611359 ENSP00000483222
ENST00000613065 ENSP00000482703
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F5H2M4
UniProt Splice Variant
Entrez Gene 9534
UniGene
RefSeq NM_001278661 NM_001278662 NM_001278677 XM_005260167 NM_001278663 NM_001278664 NM_001278665 NM_001278678 NM_203282 XM_005260168 XM_006722948 XM_006722949
HUGO HGNC:13047
OMIM 604768
CCDS CCDS74323 CCDS32983 CCDS62622 CCDS62623 CCDS74324
HPRD
IMGT
EMBL AC073534 AC092279
GenPept
RNA Seq Atlas 9534

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca