Version 5.4
Homo sapiens Gene: ART3
Summary
InnateDB Gene IDBG-25138.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ART3
Gene Name ADP-ribosyltransferase 3
Synonyms ARTC3
Species Homo sapiens
Ensembl Gene ENSG00000156219
Encoded Proteins
IDBP-25140
ADP-ribosyltransferase 3
IDBP-25142
ADP-ribosyltransferase 3
IDBP-25144
ADP-ribosyltransferase 3
IDBP-480070
ADP-ribosyltransferase 3
IDBP-482892
ADP-ribosyltransferase 3
IDBP-482696
ADP-ribosyltransferase 3
IDBP-485414
ADP-ribosyltransferase 3
IDBP-482451
ADP-ribosyltransferase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:76011184-76112802
Strand Forward strand
Band q21.1
Transcripts
ENST00000341029 ENSP00000343843
ENST00000349321 ENSP00000304313
ENST00000355810 ENSP00000348064
ENST00000395688
ENST00000513353 ENSP00000421345
ENST00000510669
ENST00000513122 ENSP00000422287
ENST00000504914 ENSP00000421431
ENST00000513494
ENST00000510423 ENSP00000425327
ENST00000506667
ENST00000504112
ENST00000506313
ENST00000511188 ENSP00000422249
ENST00000510863
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity
Biological Process
GO:0006471 protein ADP-ribosylation
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0031225 anchored component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034842
View Gene Order
ENSBTAG00000010954
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.731997
RefSeq NM_001130016 NM_001130017 NM_001179 XM_005262999 XM_006714218 XM_006714219 XM_006714220
HUGO
OMIM
CCDS CCDS3575 CCDS47079 CCDS47080
HPRD 04363
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca