Version 5.4
Mus musculus Gene: Hoxa3
Summary
InnateDB Gene IDBG-251785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hoxa3
Gene Name homeobox A3
Synonyms Hox-1.5; Mo-10
Species Mus musculus
Ensembl Gene ENSMUSG00000079560
Encoded Proteins
IDBP-251787
homeobox A3
IDBP-537800
homeobox A3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105997:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:52169062-52213336
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000114434 ENSMUSP00000110077
ENSMUST00000134831 ENSMUSP00000114711
ENSMUST00000148446
ENSMUST00000142764
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0071837 HMG box domain binding
Biological Process
GO:0001525 angiogenesis
GO:0001974 blood vessel remodeling
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0009887 organ morphogenesis
GO:0009952 anterior/posterior pattern specification
GO:0010159 specification of organ position
GO:0021615 glossopharyngeal nerve morphogenesis
GO:0030878 thyroid gland development
GO:0048538 thymus development
GO:0048645 organ formation
GO:0048704 embryonic skeletal system morphogenesis
GO:0048706 embryonic skeletal system development
GO:0051216 cartilage development
GO:0060017 parathyroid gland development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105997
View Gene Order
ENSBTAG00000008139
Not yet available
Cross-References
SwissProt
TrEMBL D3YV38
UniProt Splice Variant
Entrez Gene 15400
UniGene Mm.159945 Mm.71533
RefSeq NM_010452
OMIM
CCDS CCDS20140
HPRD
IMGT
MGI ID MGI:96175
MGI Symbol Hoxa3
EMBL AC015583 AC091106
GenPept
RNA Seq Atlas 15400

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca