Homo sapiens Gene: MRPS36
Summary
InnateDB Gene IDBG-25475.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPS36
Gene Name mitochondrial ribosomal protein S36
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134056
Encoded Proteins
mitochondrial ribosomal protein S36
mitochondrial ribosomal protein S36
mitochondrial ribosomal protein S36
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:69217760-69230129
Strand Forward strand
Band q13.2
Transcripts
ENST00000256441 ENSP00000256441
ENST00000507022
ENST00000512880 ENSP00000423659
ENST00000503793
ENST00000602380 ENSP00000473310
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_033281
HUGO
OMIM
CCDS CCDS34174
HPRD 17600
IMGT
EMBL
GenPept
RNA Seq Atlas