Version 5.4
Homo sapiens Gene: GDAP1
Summary
InnateDB Gene IDBG-25897.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GDAP1
Gene Name ganglioside induced differentiation associated protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104381
Encoded Proteins
IDBP-25899
ganglioside-induced differentiation-associated protein 1
IDBP-372623
ganglioside-induced differentiation-associated protein 1
IDBP-474406
ganglioside-induced differentiation-associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:74321130-74488872
Strand Forward strand
Band q21.11
Transcripts
ENST00000220822 ENSP00000220822
ENST00000434412 ENSP00000417006
ENST00000521096
ENST00000520797
ENST00000523640
ENST00000524366
ENST00000522568 ENSP00000430136
ENST00000524195
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 8 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000266 mitochondrial fission
GO:0006626 protein targeting to mitochondrion
GO:0008219 cell death
GO:0032526 response to retinoic acid
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0031307 integral component of mitochondrial outer membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025777
View Gene Order
ENSBTAG00000012608
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.168950
RefSeq NM_001040875 NM_018972
HUGO
OMIM
CCDS CCDS34911 CCDS47877
HPRD 05963
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca