Version 5.4
Homo sapiens Gene: BMP2K
Summary
InnateDB Gene IDBG-26183.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BMP2K
Gene Name BMP2 inducible kinase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138756
Encoded Proteins
IDBP-26185
BMP2 inducible kinase
IDBP-26189
BMP2 inducible kinase
IDBP-479396
BMP2 inducible kinase
IDBP-480074
BMP2 inducible kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:78776342-78916372
Strand Forward strand
Band q21.21
Transcripts
ENST00000335016 ENSP00000334836
ENST00000389010 ENSP00000373662
ENST00000502871 ENSP00000421768
ENST00000505725
ENST00000515075
ENST00000502613 ENSP00000424668
ENST00000507670
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 9 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019208 phosphatase regulator activity
Biological Process
GO:0006468 protein phosphorylation
GO:0030500 regulation of bone mineralization
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034663
View Gene Order
ENSBTAG00000001126
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.732528 Hs.732586
RefSeq NM_017593 NM_198892
HUGO
OMIM
CCDS CCDS34019 CCDS47083
HPRD 09828
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca