Version 5.4
Mus musculus Gene: Wdr92
Summary
InnateDB Gene IDBG-262021.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr92
Gene Name WD repeat domain 92
Synonyms AI553587; HZGJ
Species Mus musculus
Ensembl Gene ENSMUSG00000078970
Encoded Proteins
IDBP-151782
WD repeat domain 92
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000243667:
This gene encodes a protein with two WD40 repeat domains thought to be involved in an apoptosis via activation of caspase-3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:17182107-17233796
Strand Forward strand
Band A2
Transcripts
ENSMUST00000046955 ENSMUSP00000040938
ENSMUST00000151431
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000243667
View Gene Order
ENSBTAG00000010595
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_212636
Signaling by Wnt pathway
REACT_205369
Signaling by GPCR pathway
REACT_205490
DARPP-32 events pathway
REACT_219199
Activation of BH3-only proteins pathway
REACT_213138
Immune System pathway
REACT_216829
FCERI mediated Ca+2 mobilization pathway
REACT_209727
Ca2+ pathway pathway
REACT_214353
Signal Transduction pathway
REACT_206800
beta-catenin independent WNT signaling pathway
REACT_222195
Intrinsic Pathway for Apoptosis pathway
REACT_219580
Activation of BAD and translocation to mitochondria pathway
REACT_219672
Opioid Signalling pathway
REACT_216714
Innate Immune System pathway
REACT_225357
Fc epsilon receptor (FCERI) signaling pathway
REACT_219454
Apoptosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BGF3
TrEMBL
UniProt Splice Variant
Entrez Gene 103784
UniGene Mm.298132
RefSeq NM_178909
OMIM
CCDS CCDS24450
HPRD
IMGT
MGI ID MGI:2144224
MGI Symbol Wdr92
EMBL AK033294 AK088218 AL713926 BC096540
GenPept AAH96540 BAC28225 BAC40217 CAI51914
RNA Seq Atlas 103784

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca