Version 5.4
Mus musculus Gene: Zfp59
Summary
InnateDB Gene IDBG-264760.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp59
Gene Name zinc finger protein 59
Synonyms Mfg-2; Mfg2
Species Mus musculus
Ensembl Gene ENSMUSG00000078779
Encoded Proteins
IDBP-264764
zinc finger protein 59
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Krueppel-associated box (KRAB) is a domain of around 75 amino acids found in the N-terminal portion of about one third of eukaryotic Krueppel-type C2H2 zinc finger proteins (ZFPs). The KRAB domain functions as a transcriptional repressor when tethered to the template DNA by a DNA-binding domain. Although the function of KRAB-ZFPs is largely unknown, they appear to play important roles during cell differentiation and development. This gene encodes a protein belonging to the Krueppel family of C2H2-type zinc finger proteins and has been shown to accumulate in the nuclei of mature sperm in association with the nuclear matrix. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27842855-27855086
Strand Forward strand
Band A3
Transcripts
ENSMUST00000108331 ENSMUSP00000103968
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL F8VPX4
UniProt Splice Variant
Entrez Gene 22717
UniGene
RefSeq NM_011762 XM_006539744
OMIM
CCDS CCDS39851
HPRD
IMGT
MGI ID MGI:99206
MGI Symbol Zfp59
EMBL AC139063 AC164532
GenPept
RNA Seq Atlas 22717

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca