InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: ATP6V0D2

Summary

InnateDB Gene

IDBG-27527.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP6V0D2

Gene Name

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000147614

Encoded Proteins

IDBP-27529

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2

IDBP-476197

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2

IDBP-482782

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:85987323-86154228

Strand

Forward strand

Band

q21.3

Transcripts

ENST00000285393	ENSP00000285393
ENST00000521564	ENSP00000429731
ENST00000523635	ENSP00000428382

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015078	hydrogen ion transmembrane transporter activity

Biological Process

GO:0006879	cellular iron ion homeostasis
GO:0008286	insulin receptor signaling pathway
GO:0015991	ATP hydrolysis coupled proton transport
GO:0033572	transferrin transport
GO:0051701	interaction with host
GO:0055085	transmembrane transport
GO:0090382	phagosome maturation

Cellular Component

GO:0005768	endosome
GO:0005769	early endosome
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0016324	apical plasma membrane
GO:0016471	vacuolar proton-transporting V-type ATPase complex
GO:0030670	phagocytic vesicle membrane
GO:0033179	proton-transporting V-type ATPase, V0 domain
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000028238

View Gene Order

ENSBTAG00000021092

Not yet available

Pathways

NETPATH

REACTOME

REACT_25283

Transferrin endocytosis and recycling pathway

REACT_25060

Iron uptake and transport pathway

REACT_1109

Insulin receptor recycling pathway

REACT_498

Signaling by Insulin receptor pathway

REACT_121256

Phagosomal maturation (early endosomal stage) pathway

REACT_15518

Transmembrane transport of small molecules pathway

REACT_111102

Signal Transduction pathway

REACT_121237

Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway

REACT_116125

Disease pathway

KEGG

hsa05110

Vibrio cholerae infection pathway

hsa05120

Epithelial cell signaling in Helicobacter pylori infection pathway

hsa00190

Oxidative phosphorylation pathway

hsa04142

Lysosome pathway

hsa04966

Collecting duct acid secretion pathway

hsa04145

Phagosome pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.436360 Hs.583941 Hs.709047

RefSeq

NM_152565

HUGO

OMIM

CCDS

CCDS6241

HPRD

16522

IMGT

EMBL

GenPept

RNA Seq Atlas