Version 5.4
Homo sapiens Gene: SLC44A2
Summary
InnateDB Gene IDBG-27872.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC44A2
Gene Name solute carrier family 44, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000129353
Encoded Proteins
IDBP-27876
solute carrier family 44, member 2
IDBP-295165
solute carrier family 44, member 2
IDBP-763649
IDBP-766092
IDBP-763470
IDBP-766044
IDBP-760564
IDBP-761524
IDBP-764501
IDBP-762657
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:10602457-10644559
Strand Forward strand
Band p13.2
Transcripts
ENST00000335757 ENSP00000336888
ENST00000407327 ENSP00000385135
ENST00000588465
ENST00000592293 ENSP00000466612
ENST00000586078 ENSP00000466664
ENST00000586549 ENSP00000468812
ENST00000588393
ENST00000588688 ENSP00000467552
ENST00000590382 ENSP00000468691
ENST00000590857 ENSP00000465547
ENST00000589561
ENST00000588409 ENSP00000468070
ENST00000588214
ENST00000590475
ENST00000591194 ENSP00000466575
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0015220 choline transmembrane transporter activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0007165 signal transduction
GO:0015871 choline transport
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000057193
View Gene Order
ENSBTAG00000002628
Not yet available
Pathways
NETPATH
REACTOME
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_121238
Synthesis of PC pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.534560 Hs.635663
RefSeq NM_001145056 NM_020428 XM_005259998
HUGO
OMIM
CCDS CCDS12245 CCDS54216
HPRD 16198
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca