Version 5.4
Homo sapiens Gene: OR52B4
Summary
InnateDB Gene IDBG-281517.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR52B4
Gene Name olfactory receptor, family 52, subfamily B, member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000221996
Encoded Proteins
IDBP-295088
olfactory receptor, family 52, subfamily B, member 4
IDBP-808501
olfactory receptor, family 52, subfamily B, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type polymorphic_pseudogene
Genomic Location Chromosome 11:4367263-4368386
Strand Reverse strand
Band p15.4
Transcripts
ENST00000408920 ENSP00000386160
ENST00000624801 ENSP00000485530
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050890 cognition
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_15488
Olfactory Signaling Pathway pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q8NGK2
TrEMBL
UniProt Splice Variant
Entrez Gene 143496
UniGene Hs.447463
RefSeq NM_001005161
HUGO HGNC:15209
OMIM
CCDS CCDS41609
HPRD 15007
IMGT
EMBL AB065792 AC009758 BK004256 CH471064
GenPept BAC06011 DAA04654 EAW68847
RNA Seq Atlas 143496

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca