Homo sapiens Gene: CKLF | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-281643.5 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | CKLF | ||||||||||||||||||
Gene Name | chemokine-like factor | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000217555 | ||||||||||||||||||
Encoded Proteins |
chemokine-like factor
chemokine-like factor
chemokine-like factor
chemokine-like factor
chemokine-like factor
chemokine-like factor
chemokine-like factor
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 16:66552563-66566251 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q21 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | E9PLU7 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 51192 | ||||||||||||||||||
UniGene | |||||||||||||||||||
RefSeq | NM_001040138 NM_016326 NM_016951 NM_181640 NM_181641 NM_001202509 NM_001204098 NM_001204099 | ||||||||||||||||||
HUGO | HGNC:13253 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS10806 CCDS10807 CCDS10808 CCDS10809 CCDS45502 CCDS56000 CCDS73898 CCDS73899 | ||||||||||||||||||
HPRD | 16718 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AC010542 | ||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | 51192 | ||||||||||||||||||