Version 5.4
Homo sapiens Gene: OR2A1
Summary
InnateDB Gene IDBG-281713.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR2A1
Gene Name olfactory receptor, family 2, subfamily A, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000221970
Encoded Proteins
IDBP-293951
olfactory receptor, family 2, subfamily A, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:144318125-144319057
Strand Forward strand
Band q35
Transcripts
ENST00000408951 ENSP00000386175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_15488
Olfactory Signaling Pathway pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q8NGT9
TrEMBL H9XFA9 H9XFB0 H9XFB1 H9XFB2
UniProt Splice Variant
Entrez Gene 402317
UniGene Hs.528398
RefSeq NM_001005287 XM_005249986 XM_005249987
HUGO HGNC:8229
OMIM
CCDS CCDS43673
HPRD
IMGT
EMBL AB065692 AF399597 BK004217 BK004418 JQ511940 JQ511941 JQ511942 JQ511943
GenPept AAK95082 AFG72975 AFG72976 AFG72977 AFG72978 BAC05915 DAA04615 DAA04816
RNA Seq Atlas 346528 402317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca