Version 5.4
| Homo sapiens Gene: HEPN1 | |||
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| Summary | |||
| InnateDB Gene | IDBG-281735.5 | ||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||
| Gene Symbol | HEPN1 | ||
| Gene Name | hepatocellular carcinoma, down-regulated 1 | ||
| Synonyms | |||
| Species | Homo sapiens | ||
| Ensembl Gene | ENSG00000221932 | ||
| Encoded Proteins |
hepatocellular carcinoma, down-regulated 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||
| Entrez Gene | |||
| Summary |
This gene is expressed in the liver, and encodes a short peptide that is localized predominantly to the cytoplasm. Transient transfection studies showed that expression of this gene significantly inhibited cell growth, and it may have a role in apoptosis. Expression of this gene is downregulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). Also to note is that this gene maps to the 3'-noncoding region of HEPACAM gene (GeneID:220296) on the antisense strand (PMID:15885354). [provided by RefSeq, Aug 2011] |
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| Gene Information | |||
| Type | Protein coding | ||
| Genomic Location | Chromosome 11:124919244-124920677 | ||
| Strand | Forward strand | ||
| Band | q24.2 | ||
| Transcripts |
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| Interactions | |||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||
| No orthologs found for this gene | |||
| Cross-References | |||
| SwissProt | Q6WQI6 | ||
| TrEMBL | |||
| UniProt Splice Variant | |||
| Entrez Gene | 641654 | ||
| UniGene | |||
| RefSeq | NM_001037558 | ||
| HUGO | HGNC:34400 | ||
| OMIM | 611641 | ||
| CCDS | CCDS41729 | ||
| HPRD | |||
| IMGT | |||
| EMBL | AY275431 BC037810 | ||
| GenPept | AAQ19120 | ||
| RNA Seq Atlas | 641654 | ||