Version 5.4
Homo sapiens Gene: ITGAD
Summary
InnateDB Gene IDBG-28378.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITGAD
Gene Name integrin, alpha D
Synonyms ADB2; CD11D
Species Homo sapiens
Ensembl Gene ENSG00000156886
Encoded Proteins
IDBP-28384
integrin, alpha D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:31393312-31426505
Strand Forward strand
Band p11.2
Transcripts
ENST00000389202 ENSP00000373854
ENST00000444228
ENST00000567308
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0030198 extracellular matrix organization
GO:0050798 activated T cell proliferation
Cellular Component
GO:0005886 plasma membrane
GO:0008305 integrin complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070369
View Gene Order
ENSBTAG00000019524
Not yet available
Pathways
NETPATH
REACTOME
REACT_13552
Integrin cell surface interactions pathway
REACT_118779
Extracellular matrix organization pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
INOH
INOH website
Integrin signaling pathway pathway
PID NCI
integrin_cs_pathway
Integrin family cell surface interactions
integrin2_pathway
Beta2 integrin cell surface interactions
Cross-References
SwissProt Q13349
TrEMBL Q59H14
UniProt Splice Variant
Entrez Gene 3681
UniGene Hs.679163
RefSeq NM_005353
HUGO HGNC:6146
OMIM 602453
CCDS CCDS32438
HPRD
IMGT
EMBL AB208945 AF187881 U37028 U40274 U40275 U40276 U40277 U40278 U40279
GenPept AAB38547 AAB60634 AAB60635 AAB60636 AAB60637 AAB60638 AAF62875 BAD92182
RNA Seq Atlas 3681

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca