Version 5.4
Homo sapiens Gene: HPCAL1
Summary
InnateDB Gene IDBG-28496.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HPCAL1
Gene Name hippocalcin-like 1
Synonyms BDR1; HLP2; VILIP-3
Species Homo sapiens
Ensembl Gene ENSG00000115756
Encoded Proteins
IDBP-28500
hippocalcin-like 1
IDBP-28502
hippocalcin-like 1
IDBP-363348
hippocalcin-like 1
IDBP-363363
hippocalcin-like 1
IDBP-363367
hippocalcin-like 1
IDBP-809011
hippocalcin-like 1
IDBP-809014
hippocalcin-like 1
IDBP-809015
hippocalcin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:10302889-10427617
Strand Forward strand
Band p25.1
Transcripts
ENST00000307845 ENSP00000310749
ENST00000381765 ENSP00000371184
ENST00000423674 ENSP00000413689
ENST00000419810 ENSP00000416359
ENST00000422133 ENSP00000388856
ENST00000620771 ENSP00000483786
ENST00000622018 ENSP00000482993
ENST00000613496 ENSP00000478231
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000071379
View Gene Order
ENSBTAG00000004259
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 3241
UniGene Hs.467696 Hs.580427
RefSeq NM_001258357 NM_001258358 NM_001258359 NM_002149 NM_134421 XM_005246160
HUGO HGNC:5145
OMIM 600207
CCDS CCDS1671
HPRD 02564
IMGT
EMBL
GenPept
RNA Seq Atlas 3241

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca