Version 5.4
Homo sapiens Gene: NSA2
Summary
InnateDB Gene IDBG-28730.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NSA2
Gene Name NSA2 ribosome biogenesis homolog (S. cerevisiae)
Synonyms CDK105; HCL-G1; HCLG1; HUSSY29; TINP1
Species Homo sapiens
Ensembl Gene ENSG00000164346
Encoded Proteins
IDBP-28732
NSA2 ribosome biogenesis homolog (S. cerevisiae)
IDBP-483944
NSA2 ribosome biogenesis homolog (S. cerevisiae)
IDBP-809782
NSA2 ribosome biogenesis homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nucleolar protein involved in cell cycle regulation and proliferation. This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein, which is involved in large ribosomal subunit biogenesis. The encoded protein is found at elevated levels in diabetic nephropathy. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:74766991-74780113
Strand Forward strand
Band q13.3
Transcripts
ENST00000296802 ENSP00000296802
ENST00000514918
ENST00000513356
ENST00000515524 ENSP00000427266
ENST00000610426 ENSP00000483484
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005730 nucleolus
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060739
View Gene Order
ENSBTAG00000003066
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001271665 NM_014886
HUGO
OMIM
CCDS CCDS4025 CCDS75260
HPRD 18191
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca